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[1] Some compounders suggest adding B12 to tirzepatide formulations based on theoretical concerns about vitamin B12 absorption, though it's important to note that clinical evidence specifically linking tirzepatide to B12 deficiency is lacking

Options include: Fortified foods : Nutritional yeast, plant-based milk alternatives, breakfast cereals, and meat substitutes fortified with B12 (check labels for content) Supplements : Daily supplements of 10 mcg or weekly doses of 2,000 mcg ensure adequate intake, as recommended by the British Dietetic Association The body absorbs approximately 50% of a 12 mcg dose but only about 1% of a 1,000 mcg dose through passive diffusion

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