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We observed a reduction TH1-related cytokines after GE2 treatment in females ( p = 0.016), but not in males ( p = 0.474

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Month 2-3: Accelerated Weight Loss and Dose Optimization Months two and three represent the most dramatic weight loss period for most patients, with typical losses of 5-10 pounds per month during this window

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Proactive management strategies include staying well-hydrated, eating smaller, lower-fat meals, and considering stool softeners or hydration optimization to address constipationthe most persistent side effect at this dose tier