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Physical examination may reveal tenderness over the chest wall or signs of reflux disease

In response to nutrients, enteroendocrine L-cells and K-cells produce and release the incretin hormones including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), respectively [2]

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In the PIONEER 10 clinical trial, the outcomes of patients on varying doses of oral semaglutide versus dulaglutide were compared and included side effects