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Patients were categorized into four treatment groups: (i) both SGLT2-I and GLP-1RA, (ii) SGLT2-I only, (iii) GLP-1RA only, and (iv) neither medication

Avoid caffeine after noon and alcohol before bed, as both interrupt sleep patterns

Evidence Trials investigating the use of GLP-1 RAs currently approved in the United States in addition to basal insulin versus an active comparator of prandial insulin are summarized in TABLE 2

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Libraries were quantified with NuQuant, quality checked using a TapeStation instrument (Agilent Technologies) and subjected to 52 bp paired-end sequencing on the NovaSeq 6000 system (Illumina)