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In the initial phase I clinical trial for MT-II conducted to evaluate the peptides safety and tanning potential, all subjects administered MT-II experienced statistically significant skin darkening [5]

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The main difference is that MT-1 is a straight peptide that is a full clone of endogenous -MSH while MT-2 is a circular peptide that's just a partial copy of the version made naturally in the body

The effect of high mobility group box-1 protein on cerebral edema, blood-brain barrier, oxidative stress and apoptosis in an experimental traumatic brain injury model

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