The gold standard for monitoring and diagnosing liver disease is a liver biopsy, which is invasive and can be painful or cause complications
It's a long story
Step 4: Be consistent
Mitochondrial rRNA methylation by Mettl15 contributes to the exercise and learning capability in mice [J]
This outstanding specificity and minimal interference eliminate the need for extensive sample preparation, yielding practical advantages such as faster processing times, reduced reagent consumption, lower risk of analyte loss, and improved laboratory workflow efficiency

Gaussian 16, Revision C01, Frisch MJ, Trucks GW, Schlegel HB, Scuseria GE, Robb MA, Cheeseman JR, Scalmani G, Barone V, Petersson GA, Nakatsuji H, Li X, Caricato M, Marenich AV, Bloino J, Janesko BG, Gomperts R, Mennucci B, Hratchian HP, Ortiz JV, Izmaylov AF, Sonnenberg JL, Williams-Young D, Ding F, Lipparini F, Egidi F, Goings J, Peng B, Petrone A, Henderson T, Ranasinghe D, Zakrzewski VG, Gao J, Rega N, Zheng G, Liang W, Hada M, Ehara M, Toyota K, Fukuda R, Hasegawa J, Ishida M, Nakajima T, Honda Y, Kitao O, Nakai H, Vreven T, Throssell K, Montgomery JA, Peralta J, Ogliaro JE, Bearpark F, Heyd MJ, Brothers JJ, Kudin EN, Staroverov KN, Keith VN, Kobayashi TA, Normand R, Raghavachari J, Rendell K, Burant AP, Iyengar JC, Tomasi SS, Cossi J, Millam M, Klene JM, Adamo M, Cammi C, Ochterski R, Martin JWRL, Morokuma K, Farkas O