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The purified TRF1 TRFH domain was then concentrated by centrifugation on a Vivaspin Turbo 15 centrifugal concentrator (10 kDa MWCO) to either ~ 3 mg/mL for NMR studies or ~ 30 mg/mL for crystallisation before flash-freezing and storage at 80 C (Supplementary Fig

Therapeutic Research Protocol Dose: 0.5 0.75 mg (variant 5 mg pen = 2030 clicks / variant 10 mg pen = 1015 clicks) Duration: 4 6 weeks Frequency: Daily Cycle Interval: 4 weeks off before next cycle Goal / Description: Used in muscle or tendon repair studies

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