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To minimize irritation & purging: 1
doi: 10.1002/oby.21577 243 NunnEJaiswalNGavinMUeharaKStefkovichMDrareniKet al
Especially at night, this can lead to regurgitation (backflow of gastric juices) and so-called micro-aspirations (cough, lung problems, hoarseness)
An important focus for future research is to elucidate the pathways by which these pleiotropic compounds exert their effects on AD/ADRD and the implications for such factors as dose and timing of treatment (Majumder et al., 2011)
This drug was clinically developed and called Glucophage (glucose eater)
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