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Lean body mass

Beyond standard metabolic monitoring (weight, blood pressure, glucose, lipids), providers should regularly assess binge eating frequency, eating disorder cognitions, mood symptoms, and quality of life

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The percentage of patients who discontinued due to ineffective therapy was 0.9% in the liraglutide injection 1.8 mg + metformin + glimepiride treatment group, 0.4% in the insulin glargine + metformin + glimepiride treatment group, and 11.3% in the placebo + metformin + glimepiride treatment group

Meanwhile, structural damage was observed in mitochondria, accompanied by increases in ROS and malondialdehyde (MDA), as well as decreases in GSH and GPX4