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Circ Res 113(2):115125

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Crataegus special extract WS 1442 increases force of contraction in human myocardium cAMP-independently

In a small randomized crossover trial, daily 15mg of pioglitazone in CAPD patients (both with and without DM) showed improved insulin resistance, adipokine balance, with reduced markers of inflammation.40 In the diabetic PD population, pioglitazone may be continued without any dose adjustments on PD-free days without increases risk of hypoglycemia.24 The main drawback to its use is related to its adverse effect profile on fluid retention, meaning that it is usually an alternative to other agents with a better safety profile

Zhou H, Lin H, Chen S et al (2014) Inhibition of the Arabidopsis salt overly sensitive pathway by 14-3-3 proteins

& Donnelly, L