However, doing the same exercises every time without any alterations can create a plateau
The dual GIP/GLP-1 mechanism appears to be more effective than GLP-1 alone, which is why researchers continue developing multi-receptor agonists
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Abbreviations ABC ATP-binding cassette ABCA1 ATP-binding cassette transporter A1 GLP-1 glucagon-like peptide-1 GSIS glucose-stimulated insulin secretion HDL high-density lipoprotein HDL-C high-density lipoprotein cholesterol H&E Hematoxylin and eosin IHC immunohistochemical IP immunoprecipitation LDL low-density lipoprotein LSG laparoscopic sleeve gastrectomy LXR liver X receptor OGTT oral glucose tolerance test PARP poly ADP-ribose polymerase RCT reverse cholesterol transport RYGB Roux-en-Y gastric bypass STZ streptozotocin TC total cholesterol TG total triglyceride T2DM type 2 diabetes
One suggested practice to managing GI AEs is the Three Es method, which comprises 1) education and explanation, 2) escalation to an appropriate dose, and 3) effective management of GI AEs
J Diabetes Investig (2016) 7:505