The overall food budget is not shrinking at the same rate as volumes
More isn't always better
Nearly all patients with PCOS who were prescribed semaglutide or tirzepatide also had obesity and/or diabetes, conditions for which these medications have FDA-approved indications
By acting on both GLP-1 and GIP receptors, it enhances insulin secretion and reduces appetite, making it a promising option for those seeking better health control
Safety The safety profile of retatrutide was generally favorable, although some adverse events were more common in the treatment groups
335,336 Further, the GLP-1/GIP dual-agonist tested in this study, MAR709, lost its superior efficacy on body weight and food intake over GLP-1 in the CNS-GIPR knockout mice, suggesting that this dual-agonist mediates part of its action via the CNS-GIPR