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doi: 10.1016/j.mce.2013.01.016 58 WuJMinikesAMGaoMBianHLiYStockwellBRet al

That FDA approval means it has undergone rigorous clinical testing with robust data on visceral fat reduction, and the mechanistic basis for its effects applies equally to menopausal visceral fat accumulation

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Preclinical studies have shown a genetic deletion of antioxidant enzymes (e.g., SOD, GPx) inducing HTN in mice (Rodrigo et al., 2021)

Mamas MA, Bays H, Li R, Upadhyay N, et al