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Work with your prescribing provider to understand your options, which may include transitioning to brand-name products or continuing with compounded formulations if they remain legally available through the medical necessity exemption or other regulatory pathways

People are experimenting clinically to see if spreading doses out or gradually tapering down can help maintain weight loss. That lack of FDA approval has not stopped interest from growing

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"For retatrutide, the findings from TRIUMPH-4 are encouraging, and with seven additional phase 3 readouts expected in 2026, we believe retatrutide could become an important option for patients with significant weight loss needs and certain complications, including knee osteoarthritis," a Lilly spokesperson said in a statement to Fox News Digital

Retatrutide is a triple agonist, meaning it also hits GIP and glucagon receptors on top of GLP-1