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Another 2023 study found similar improvements with the combination of GLP-1 and exercise but also noted lower markers of inflammation and improved metabolic syndrome

Weeks 58: Peak Appetite Suppression and Visible Changes The second month is when most people see the most dramatic shift in appetite and behavior

That said, both medications can cause gastrointestinal side effects like nausea, so you may notice these are more pronounced when starting Wegovy while already on sertraline

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Many studies indicate an association between increased VEGF expression in the brain, brain hypoperfusion, and increased BBB permeability, which increases unwanted angiogenesis, and may favor the occurrence of neurodegenerative diseases (Chen et al