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doi: 10.1038/s41586-018-0697-7 121 RiessCShokraieFClassenCFKreikemeyerBFiedlerTJunghanssCet al

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In regulating the response to inflammation of the endothelium, dulaglutide counteracts high glucose-induced activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome and suppresses maturation and release of IL-1 and IL-18