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Biochemistry of metallothionein

Such decrease in levels is the result of diseases like exocrine pancreatic insufficiency

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Based on previous studies [8, 19, 20] it is conceivable that the increases in lean mass we observed for GSH + CIT in the present study could have occurred due to increases in muscle protein synthesis, and this could be linked to NO-induced increases in cGMP [19]

[PubMed] [EuropePMC] 50

The dose is further escalated (titrated) by increasing by 2.5 mg every 4 weeks until reaching the maintenance dosage