MOTS-c is a mitochondrial-derived peptide that influences how cells use glucose and fat for energy, described as mimicking some of the metabolic effects of exercise at a cellular level, with reported benefits including increased stamina and reduced belly fat
The mechanisms behind the renoprotective effects of GLP-1 RAs involve anti-albuminuric, anti-inflammatory, natriuresis, anti-atherogenic, and anti-oxidant effects through protein kinase A signaling, induction of natriuresis by inhibiting sodium-hydrogen exchanger 3, and a reduction in hyperfiltration 27,30,31
Its important to note that its generally not recommended for women to take GLP-1s or other weight loss medications while looking to get pregnant, are currently pregnant, or are breastfeeding
Exenatide is a synthetic form of a protein originally isolated from the saliva of the Gila monster (poisonous lizard that lives in the deserts of Arizona)(Triplitt & Chiquette, 2003)
The New England Journal of Medicine, 391 (2), 109121
Among the many updated and iterative products, drugs such as GLP-1 are definitely the most shining ones