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The most commonly reported side effects are typically mild and transient, occasionally including minor gastrointestinal upset, nausea, or heartburn, particularly if the supplements are taken on an empty stomach or in excessively high doses all at once

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In laboratory settings, anthraquinones causes apoptosis of guinea pig enterocytes leading to lipofuscin accumulation

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Shi H, Xu K, Huang M, Mao M, Ou J

FoB or MZB cells were seeded in XF Seahorse RPMI medium at 10 6 /well on Seahorse XFe96 culture plates pre-coated with Cell-Tak