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the same dose of 20 mg can be tried for 72 hrs or higher for 1- 3 times a week application

The strongest, proven benefits for skin come from topical application

Recent studies (Maleki Dizaj et al., 2022) noted that nano-formulations of curcumin substantially enhance its solubility, absorption, cellular uptake, and tissue distribution, leading to markedly increased bioavailability in various conditions, including neurodegenerative, cardiovascular, and metabolic disorders

The ratio between these forms serves as an important indicator of cellular oxidative stress

2009 documented similar timelines in their photoaged-skin RCT 10

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