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The plurality of intracellular proteins is degraded by the ubiquitin (Ub)proteasome pathway (UPP)

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de Lima e Silva C, van Haren C, Mainardi G, de Rooij W, Ligtelijn M, van Straalen NM, van Gestel CAM (2021) Bringing ecology into toxicology: life-cycle toxicity of two neonicotinoids to four different species of springtails in LUFA 2.2 natural soil

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To perfectly replicate the physiological baseline of the human "uricase deficiency," the Uox KO mouse was developed