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UVB induces damage to skin mainly by oxidative stress, inflammation, and collagen degradation

For this reason, glutathione remains a main focus in research on antioxidants, cell defense, and body processes

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Where liver-derived IGF-1 has broad systemic effects, MGF acts locally at the site of mechanical tissue damage

FIGURE 7 3.7 GHK-Cu suppresses inflammatory cytokines partly via STAT3 inhibition We also explored the role of STAT3 in modulating inflammatory factor expression by GHK-Cu in LPS-stimulated MPMs transfected with siSTAT3

This led to GHK initially being classified as a liver cell growth factor