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In clinical trials, semaglutide produced average total body weight loss of roughly 15% (STEP program), while tirzepatide produced average reductions in the range of about 1521% (SURMOUNT program)

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Here we show that the antioxidant glutathione is inextricably linked to redox-active processes that facilitate melanin and titan cell production, as well as survival in macrophages and virulence in a murine model of cryptococcosis