All-cause mortality Compared with placebo, tirzepatide and the GLP-1RA class significantly reduced the risk of all-cause mortality (HR 0.74, 95% CI 0.650.83 and HR 0.88, 95% CI 0.830.92, respectively)
These treatments work by stimulating collagen production and improving the texture and color of stretch marks
Some dermatologists may also recommend a triple combination cream containing hydroquinone 4%, tretinoin 0.05%, and flucinolone acetonide 0.01% in combination with oral tranexamic acid to treat melasma and lighten hyperpigmentation
Variants like C677T and A1298C can reduce enzyme efficiency, potentially leading to higher homocysteine levels and impacting processes like detoxification, neurotransmitter production, and cardiovascular health
Many patients can still use tirzepatide under closer monitoring
Doug Lucas Clinical Lead, Bone Health & Longevity Double board-certified orthopedic surgeon specializing in osteoporosis, hormonal, metabolic, and regenerative medicine