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Some patients report a slight warm sensation at the injection site or mild nausea in the first eveningthese sensations typically fade within hours

Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis

www.accessdata.fda.gov/drugsatfda_docs/label/2008/012151s062lbl.pdf

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As our subjects were recruited from a broad age range, we also decided to categorize the age groups into those younger and older than 40 years