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It has been described for roGFP1-iL that the insertion C147CL and the substitution H148S lower the thermodynamic stability of the inter-strand disulfide C147C204 resulting in a less negative E of the sensor (Lohman and Remington, E roGFP2-iL was determined through titration with LA/DHLA

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Nevertheless, one singular hypothesis cannot fully justify the complex etiology or mechanisms underlying AD (Joe and Ringman, 2019)

Gao Y, Li J, Wu Q, Wang S, Yang S, Li X, Chen N, Li L et al (2021) Tetrahydroxy stilbene glycoside ameliorates Alzheimers disease in APP/PS1 mice via glutathione peroxidase related ferroptosis

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