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Metoclopramide is the only FDA-approved drug for gastroparesis, and it carries a black box warning for tardive dyskinesia risk with long-term use

Additionally, DSIP appears to be regulated by glucocorticoids, and its signaling may interact with the MAPK cascade through homology with glucocorticoid-induced leucine zipper (GILZ), suggesting potential roles in cellular stress responses

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Intravenous cysteine administered to preterms postnatally, even in high doses, showed no harmful effects but failed to restore GSH concentration or enhance its synthesis rate

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