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Furthermore, we found that even in one-year follow up, GLP-1 can reduce the risk of osteoporosis and the HR is lower with the longer duration of follow up, which means GLP-1 RAs might have a lasting influence on bone metabolism

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Keep them separate until administration

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Watts T, Berti I, Sapone A et al (2005) Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats

These effects are due to increased growth hormone levels