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The injection of lentivirus carrying sh-lncRNA XIST plasmids reduces levels of TNF-, IL-2, and IL-6 to suppress inflammatory and damage in cartilage tissues (270)

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AMG-458 significantly inhibited tumor growth of the U-87 MG human glioblastoma xenografts and of NIH-3 T3/TPR-MET tumors with constitutive activation of c-Met [74]