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CV Outcomes in Observational Studies: CVD-REAL Registries In a large multinational study (CVD-REAL [Comparative Effectiveness of Cardiovascular Outcomes in New Users of Sodium-Glucose Cotransporter-2 Inhibitors]: 6 European countries and the United States), a treatment with SGLT-2 inhibitors versus other glucose-lowering agents was associated with a lower risk of hospitalization for HF and all-cause death (Table 6)
Amid this surge, Novo Nordisk, the company behind GLP-1 drugs Ozempic and Wegovy, has experienced a remarkable rise in its stock price, from roughly $50 per share in 2022 to upwards of $142 in June 2024
However, individual responses differ substantially based on baseline metabolic status, genetic factors, and medication adherence
Tirzepatide and retatrutide also mimic a second hormone called glucose-dependent insulinotropic polypeptide (GIP) to reduce appetite and blood sugar
Similarly, 58% of physicians surveyed said they are concerned about overreliance on AI for diagnoses, and 53% said they are worried about the risk of improper diagnosis
