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doi: 10.1038/s41467-024-53380-5 87 MajumdarRBarchiBTurlapatiSAGagneMMinochaRLongSet al

Lysyl oxidase, the copper-dependent enzyme that catalyzes the oxidative deamination of lysine residues in collagen and elastin (a step required for the cross-linking that gives mature collagen and elastin their mechanical properties), requires copper as a cofactor

Withania Somnifera , an Ayruvedic medicinal herb, contains a steroidal lactone called withaferin A, which has been investigated for its biological properties, including anti-inflammatory, anti-angiogenic, and anti-tumor actions [99]

This converts silenced Heterochromatin into active Euchromatin, allowing repair genes to be transcribed

Cortical interlaminar astrocytes are generated prenatally, mature postnatally, and express unique markers in human and nonhuman primates