A natural moisturizer thats also in our skin A super common, safe, effective and cheap molecule used for more than 50 years Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40% High-glycerin moisturizers are awesome for treating severely dry skin The main part of a moisturizing complex called Aquaxyl
Alzheimers: Drug Might Slow Decline Researchers found patients with Alzheimers who took liraglutide had 18% slower cognitive decline over the course of a year compared to those taking a placebo
Mood Disturbances and Depression: ALCAR's ability to restore neuronal energy metabolism and lipid function in the brain has been linked to antidepressant-like effects in animal models, suggesting potential support for emotional regulation
The realistic timeline: pivotal trial results by mid-2026, NDA submission by late 2026, FDA decision by mid to late 2027, and pharmacy availability by late 2027 or early 2028
It originates from the preproglucagon precursor, which undergoes enzymatic processing within intestinal L-cells, ultimately giving rise to GLP-1(1-37) and GLP-1(7-36) amide or GLP-1(7-37) peptide variants.30,31 GLP-1 is an incretin hormone that plays a pivotal role in the meticulous control of human blood glucose levels.32,33 Nevertheless, its duration of action is rather ephemeral, lasting a mere 12 min within the circulatory system under typical physiological conditions.34,35 Subsequently, GLP-1 undergoes enzymatic degradation facilitated by dipeptidyl peptidase IV (DPP-4), leading to the loss of its biological efficacy.36 GLP-1 GLP-1
IGFBP Avoidance: It successfully avoids IGF binding proteins (IGFBPs), which typically regulate and limit IGF activity, allowing it to exert an immediate, unbound effect