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doi:10.1016/j.neubiorev.2016.08.014

PMID: 15748676

10.1002/med.21257 [DOI] [PMC free article] [PubMed] [Google Scholar] Njlsson R., and Norgren S

The trans-3-hexenoic acid group sterically shields the N-terminal region from dipeptidyl peptidase IV (DPP-IV) cleavage, which is the primary route of GHRH degradation in vivo, resulting in meaningfully improved metabolic stability compared to native GHRH and sermorelin

3, below) revealed binding of 25HC to the site-II of v3 integrin, we choose fractalkine protein as a competitor since previous studies have shown that the chemokine domain (CD) of fractalkine protein (fractalkine-CD) binds to the site-II of v3 integrin 34,35

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