This trial is for adults with a BMI of 25 kg/m2 who meet the criteria for Cocaine Use Disorder, have used cocaine recently (confirmed by urine test), and can provide informed consent
One survey last year by Asken, for example, found that, among nearly 13,000 women, more than 70% of those under 29 and between 30-39 said they felt very or quite overweight even though all of the women in that subgroup had a BMI in the standard healthy range of 18.5 to 25
Investigators to bring data on glucose management with oral orforglipron Julio Rosenstock, MD, Francesco Giorgino, MD, PhD, and other panelists will discuss results from the ACHIEVE clinical trials, including ACHIEVE-3, which compared oral semaglutide and orforglipron for use in type 2 diabetes.
Evans blue concentration was determined by spectrophotometric measurement at 620 nm and expressed as g/g gingivomucosal tissue as described earlier by our group (6)
Both use the zero-calorie, zero-sugar liquid format that's become the carnitine delivery standard, and both now come in PEZ Grape and PEZ Cherry
Microbial metabolites primarily short-chain fatty acids, bile acid secondary metabolites, and tryptophan-derived indoles stimulate GLP-1 secretion from L-cells through FFAR2/FFAR3 signaling and related mechanisms (Kouraki et al., 2026)