Keep Weekly Weight Loss Under About 1% of Bodyweight A 200 lb person should lose no more than 2 lb per week
Drucker DJ (2024): Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity
Current Research and Future Directions While the potential for GLP-1 receptor agonists in addiction treatment is exciting, more research is needed to fully understand their long-term effects and effectiveness in humans
Individual factors such as baseline gut sensitivity, concurrent medications (especially metformin, which can independently cause diarrhea), and pre-existing conditions like irritable bowel syndrome significantly influence whether diarrhea develops and its severity
Potential risks may include: Overdosing, which may lead to symptoms such as nausea, vomiting, or other adverse effects
The medication works through sustained exposure over weeks and months