Application of glutathione depletion in cancer therapy: enhanced ros-based therapy, ferroptosis, and chemotherapy
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Steullet P, Neijt HC, Cunod M, Do KQ
Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV
Phenotypic and molecular spectrum of pyridoxamine-5-phosphate oxidase deficiency: a scoping review of 87 cases of pyridoxamine-5-phosphate oxidase deficiency
Published pre-clinical studies have used FOXO4-DRI to demonstrate that selective elimination of senescent cells in aged mouse models can improve a range of tissue function parameters including fitness, fur density, renal function, and liver function establishing the broader research principle that senescent cell burden contributes meaningfully to ageing tissue dysfunction and that its targeted reduction produces measurable functional benefits in experimental models
