EULARs fibromyalgia guidelines give exercise its strongest recommendation, the only treatment to reach that rating
It may modulate TCA cycle activity via secondary messengers like cAMP, though further validation is needed (263)
Gastrointestinal adverse reactions nausea, vomiting, diarrhea, abdominal pain and constipation are the most common adverse reactions in this class and the most common reason people discontinue
References Hornsby, C., Bains, J
The upper bound of the one-sided 95% confidence interval for the largest placebo adjusted, baseline-corrected QTc based on population correction method (QTcP) was below 10 ms
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