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Simultaneously, it has been observed to modulate the expression of genes for proteoglycans and glycosaminoglycans (GAGs) like decorin, which are crucial for organizing collagen fibrils and maintaining tissue hydration in engineered skin equivalents

To view a copy of this licence, visit About this article Cite this article Coden, K.M., Nguyen, D.K.K., Moorhead, R

Maintaining steady hydration and electrolyte balance is key

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However, oral supplementation of L-arginine, the precursor for NO synthesis, has been shown to be largely ineffective at increasing NO synthesis and/or bioavailability for several reasons, which makes L-citrulline much more ideal for boosting levels of L-arginine and subsequently NO