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The ongoing research mainly focuses on finding extended applications of already existing GLP-1 analogs

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However, individual responses vary considerably, and gradual dose titration alongside dietary modifications can significantly improve tolerability across all GLP-1 preparations

Diabetologia 59 , 954965 (2016)

And retatrutide (Eli Lilly, phase III ongoing) aims higher still: triple GLP-1 + GIP + glucagon activity, redefining the upper ceiling of metabolic efficacy