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Patients with pre-existing subclinical nerve issues, perhaps from metabolic stress , vitamin deficiencies, or genetic predisposition, may respond differently to GLP-1 receptor activation than neurologically healthy patients

doi: 10.1038/nchembio.2239 55 EnkeUSeyfarthLSchleussnerEMarkertUR

Khan M, Mohsin S, Khan SN, et al

While that study did not report runaway tumor growth either, the lack of a spectacular reduction in tumor size, suggests BPC-157 offers no anti-cancer benefit and it leaves open the worry that it could even accelerate malignancy under the right conditions

Oral contraceptives may be affected by the gastric motility changes associated with tirzepatide therapy

11 , eaal2171 (2018)