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Various inherited and lifestyle factors contribute to vitamin B12 deficiencies that impair such fundamental life processes as recycling of homocysteine, a potentially toxic metabolite, nerve cell signaling, mood and memory management, and healthy gene regulation (epigenetics), from pregnancy through old age

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In conclusion, taking advantage of the elevated GSH in TME, our study affords a new strategy for targeted chemotherapy of ATC with high selectivity and reduced adverse effects

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