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The comparison between ICU and non-ICU patients showed that plasma concentrations of IL-2, IL-7, IL-10, GCSF, IP10, MCP1, MIP1A and TNF were higher in ICU patients than in non-ICU patients [33]

Clinical supply

The peptides may have potential roles as adjunctive therapies or alternative treatments for patients who cannot tolerate or do not respond adequately to conventional treatments, but this should be based on careful risk-benefit analysis and appropriate patient selection

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However, there were apparent structural differences in the helical cap, especially in helices D1 (maximum shift of approximately 5 ) and D2 (Fig

Gastrointestinal adverse effects, initially viewed as limiting, were ultimately managed through dose titration and formulation design