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Study authors are generally careful to frame these effects as most pronounced within controlled research protocols that include structured training and caloric variables the literature does not describe IGF-1 LR3 as a standalone driver of fat loss independent of those conditions

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It is best employed as adjunctive therapy to medical management & works best when combined with lasers & or chemical peels

doi: 10.1007/s00018-020-03656-y 53 BedardKKrauseK-H

10.1002/ajmg.a.38494 72 Di CostanzoA.AngelicoR

Those are not interchangeable for timing, protocol interpretation, or research design