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Loss of extracellular matrix is in part due to death of fibrous cap smooth muscle cells, resulting from macrophage-derived Fas receptor ligand (195), inflammatory cytokines (196), and oxidation products (Figure 5) (197,198)

Clinical evidence and research cited herein shows that the ingredients in Acetyl-L-Carnitine may: Promotes healthy brain function Supports energy metabolism Supports healthy immune function Supports healthy response to oxidative stress Promotes balanced moods Promotes exercise capacity Ingredients 1 capsule supplies: * % Nutrient Reference Value ** No NRV Established Other Ingredients: Hydroxypropyl methylcellulose, vegetable magnesium stearate, silicon dioxide

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Additionally , these models support investigation of how cells regulate structural proteins and extracellular matrix components

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