According to the American Diabetes Association (2024), Nevada faces rising rates of diabetes and obesity, and many students, faculty and community members are navigating conversations about metabolic health, stigma and equitable access to care
Reach weight stability on GLP-1 therapy first
McCay CM, Crowell MF, Maynard LA (1935) The effect of retarded growth upon the length of life span and upon the ultimate body size
Acknowledgements This research was supported in part through a University of Michigan Developmental Research/ GI SPORE (P50 CA130810) Pilot Award
Trials including SURMOUNT-1 and SURMOUNT-2 showed dose-dependent weight loss, with 15-mg doses producing approximately 20-21% body weight reduction over 72 weeks compared to 10-15% at lower doses
Figure 3 shows the prediction-corrected VPC plots, where most observed data fell within the 95% confidence interval (CI) generated by model simulations, showing that the final model had good forecasting ability