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Discussion This study adds to the limited available data on the use of semaglutide in patients with advanced CKD and provides insight over a prolonged follow-up period exceeding three years (median 1,187 days [IQR 6021,442]), with the majority of patients receiving maintenance hemodialysis (58.8%)

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However, tirzepatide slows gastric emptying, which can affect absorption of oral medications

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Building upon this understanding, Zhang et al

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The manufacturers recommend rotating your injection sites weekly

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