6 Side Effects Impact How Long People Stay On Its no surprise that side effects, including the ones regarding brain health and cognition, impact how long people keep taking or adhere to GLP-1s
Who Should Choose Tirzepatide: Ideal Candidates: Need maximum weight loss (50+ pounds) Want most effective medication available Can afford $349-$1,069/month depending on option Have BMI 30 (or 27 with comorbidities) Plateaued on semaglutide or other medications No contraindications to GLP-1/GIP agonists Particularly Good For: Significant obesity (BMI 35) Previous weight loss medication failures Those who want best possible results Patients who tolerate GLP-1s well Cost Comparison: Value Analysis: Cost per % Body Weight Lost: Brand-Name Tirzepatide: 22.5% loss at $12,828/year Cost per %: $570 Compounded Tirzepatide (TrimRx): 22.5% loss at $4,188/year Cost per %: $186 Compounded Semaglutide (TrimRx): 14.9% loss at $2,388/year Cost per %: $160 Both compounded options offer excellent value, with semaglutide being slightly more cost-efficient per percentage lost, while tirzepatide produces greater absolute weight loss
Available from: Sandra Christensen 1 , Katie Robinson 2 , Sara Thomas 2 , Dominique R Williams 2 Dietary intake by patients taking GLP-1 and dual GIP/GLP-1 receptor agonists: A narrative review and discussion of research needs
The MHRA has not approved any GLP-1 receptor agonist for use below the labelled doses, and this approach falls outside current prescribing guidelines
They also love the accountability that helps them stay on track with their goals
Kang MW, Tangri N, Kim YC, An JN, Lee J, Li L, et al
