Overall, discontinuation rates due to side effects are low across all options
Depending on the specific drug, injections may be required: Once daily (e.g., liraglutide) Once weekly (e.g., semaglutide, dulaglutide) Most patients find the injection process straightforward after initial training from a practice nurse or diabetes specialist nurse
Without tracking, the decision often comes down to how you feel in the moment, which is not a reliable guide
Lin DSH, Lee JK, Hung CS, Chen WJ (2021) The efficacy and safety of novel classes of glucose-lowering drugs for cardiovascular outcomes: a network meta-analysis of randomised clinical trials
Pancreatitis: GLP-1s can contribute to pancreatitis, or inflammation of the pancreas that can lead to complications if left untreated
This essentially resets the clock and puts you back through the initial discomfort again