PTH enhances CYP27B1 expression via activation of the adenylyl cyclaseprotein kinase A (ACPKA) signaling pathway, thereby promoting the synthesis of active vitamin D (12)
Balercia, G., Regoli, F., Armeni, T., Koverech, A., Mantero, F., and Boscaro, M
SOD2 converts O 2 to H 2 O 2 , which is then buffered and relayed by Prx3 and GPx in concert with the Trx2/TrxR2 couple and the GSH/GSSG pool, allowing controlled redox communication with metabolic enzymes and mtDNA repair without bulk oxidative stress (Gencheva and Arnr 2022)
Most brightening effects come from long-term use , as glutathione works gradually compared to strong actives like hydroquinone
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Wei and Mojsov, 1996