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Once inside adipocytes and other metabolically active cells, the compound binds to the NNMT active site, preventing the enzyme from converting nicotinamide to 1-MNA

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In the hands of Predrag Sikirics laboratory in Zagreb and a small number of other groups, BPC-157 has produced a remarkable volume of positive animal results across an unusually wide range of tissues: gastrointestinal ulcers and fistulas, tendon and ligament transection, muscle crush injury, bone, and even nerve and vascular injury